A prepubertal giant juvenile fibroadenoma in a 12-year-old girl: Case report and brief literature review. (2017)

• Record Type: Journal Article
• Authors: Giannos, Aris; Stavrou, Sofoklis; Gkali, Christina; Chra, Eleni; Marinopoulos, Spyridon; Chalazonitis, Athanasios; Dimitrakakis, Constantine; Drakakis, Peter
• Is Part Of: International journal of surgery case reports. Volume 41(2017)
• Page Start: 427
• Page End: 430
• Publication Date: 2017
• Subjects: Fibroadenoma -- Giant juvenile fibroadenoma -- Adolescence -- Breast -- Prepuberty; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgery; Electronic journals; Periodicals; 617.005
• DOI: 10.1016/j.ijscr.2017.11.026
• Languages: English
• ISSNs: 2210-2612

Abstract

Highlights: Giant juvenile fibroadenomas are very rare and they have very low prevalence in prepubertal period. Although they should not be ruled out in differential diagnosis in premenarchal period. Breast examination in premenarchal girls and adolescents plays a pivotal role in order to prevent these peculiar giant lesions. Another remarkable point is the rapid growth of these breast lesions that should not be ruled out in the diagnostic process of the continuously growth of the adolescent breast. Abstract: Introduction: Giant juvenile fibroadenomas represent only the 0.5% of all fibroadenomas, constituting a rare condition in adolescence. In prepuberty, the presence of this condition is extremely rare. Presentation of case: We describe a rare case of a 12- year-old Caucasian girl who presented to our Hospital complaining of a palpable mass with rapid enlargement in her right breast that she had first noticed 3 months ago. Her menarche hadn't occurred yet. Discussion: Physical examination showed a giant mass of 15 × 13 cm in the right breast. The patient was further evaluated via ultrasonography showing a sole large lesion of 13 × 12 cm in the right breast. A surgical procedure under general anesthesia was performed. Histopathological findings after the surgical excision were suggestive of giant juvenile fibroadenoma. The patient has a normal breast development over a period of 9 month follow up. Conclusion: Giant juvenile fibroadenomas should be included in differential diagnosis of a breast mass in prepubertal girls despite the fact that they are very rare in prepuberty, tend to appear later during adolescence and their prevalence is lower in Caucasians. The remarkable size and the rapid growth of the lesion should not be ruled out in the diagnostic process of an adolescent breast.