Two new compounds from Cryptoporus volvatus. (June 2017)

• Record Type: Journal Article
• Authors: Zhou, Ling-Yun; Li, Pan-Pan; Wang, Jun-Ming; Lu, Bin; Hua, Yan
• Is Part Of: Phytochemistry letters. Volume 20(2017:Jun.)
• Page Start: 204
• Page End: 207
• Publication Date: 2017-06
• Subjects: Cryptoporus volvatus -- Cytotoxic activities against cancer cell lines -- Ferric reducing capacity; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2017.04.024
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Two new compounds were isolated from Cryptoporus volvatus . This type of aldehydes was reported for the first time in this genus. Compound1 exhibited strong cytotoxicity against HL-60. The two new compounds showed high ferric reducing capacity. Abstract: Two new compounds with the aldehyde group, cryptoporusal A (1) and 9-formyl-4-hydroxy-6, 9-dimethyl-1-O-β-D-xylosopyranosyl-8a, 9-dihydro-ace-naphthylen-8-one (2), were isolated from the ethyl acetate extract of the fruiting bodies of Cryptoporus volvatus (Pk.) Hubbard. Their structures were elucidated by extensive spectroscopic studies, and comparison with literature data. Furthermore, they were evaluated for their in vivo cytotoxicity against five human cancer cell lines and antioxidant activity. Compound1 exhibited strong cytotoxicity against HL-60 and both showed high ferric reducing capacity.