Polymorphism of 15 short tandem repeat loci in Hui population of Ningxia Tongxin district. (November 2017) - Ma, Xiuzi
Abstract: Objective: To investigate the polymorphism of 15 STR loci in Hui population from Ningxia Tongxin district. Methods: Identifiler Plus kit used to detect the allelic frequencies of 15 STR loci in 598 unrelated Tongxin Hui individuals, and the population genetics parameters were calculated by using statistic software. Results: The results demonstrated that all loci were found to be no deviation from Hardy-Weinberg equilibrium (P > 0.05), Heterozygosity (H) ranged from 0.637 to 0.868, matching probability ( Pm ) ranged from 0.034 to 0.213, power of discrimination (DP) ranged from 0.787 to 0.966, polymorphism information content (PIC) ranged from 0.560 to 0.850, power of exclusion (PE) ranged from 0.338 to 0.730. Conclusions: The 15 STR loci are relatively abundant in polymorphic information and suitable for paternity testing and personal identification. Highlights: Hui population of Ningxia Tongxin district accounts for 85.6% of the total county population, Tongxin is a region inhabited by the Hui people. Short tandem repeat (STR) has important significance in genetic mapping, gene diagnosis, disease screening, forensic individual identification, paternity testing and national research. This paper intends to investigate the polymorphism of 15 STR loci in Hui population from Ningxia Tongxin district, and provides basic data for the research and application of population genetics in this area.