Basic and translational neuro-ophthalmology of visually guided saccades: disorders of velocity. (2nd November 2017)

• Record Type: Journal Article
• Authors: Puri, Sushant; Shaikh, Aasef G.
• Is Part Of: Expert review of ophthalmology. Volume 12:Number 6(2017)
• Page Start: 457
• Page End: 473
• Publication Date: 2017-11-02
• Subjects: eye movements -- saccade -- saccade velocity; Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1080/17469899.2017.1395695
• Languages: English
• ISSNs: 1746-9899

Abstract

ABSTRACT: Introduction : Saccades are rapid, yoked eye movements to direct a target over fovea. The complex circuitry of saccadic eye movements has been exhaustively described. As a result clinicians can elegantly localize the pathology if it falls on the neuraxis responsible for saccades. Traditionally saccades are studied with their quantitative characteristics such as amplitude, velocity, duration, direction, latency and accuracy. Areas covered : Amongst all subtypes, the physiology of the visually guided saccades is most extensively studied. Here we will review the basic and pertinent neuro-anatomy and physiology of visually guided saccade and then discuss common or classic disorders affecting the velocity of visually guided saccades. We will then discuss the basic mechanism for saccade slowing in these disorders. Expert commentary : Prompt appreciation of disorders of saccade velocity is critical to reach appropriate diagnosis. Disorders of midbrain, cerebellum, or basal ganglia can lead to prolonged transition time during gaze shift and decreased saccade velocity.