One new cytochalasin metabolite isolated from a mangrove-derived fungus Daldinia eschscholtzii HJ001. Issue 2 (17th January 2018)

• Record Type: Journal Article
• Authors: Yang, Lu-Jia; Liao, Hai-Xia; Bai, Meng; Huang, Guo-Lei; Luo, You-Ping; Niu, Yan-Yan; Zheng, Cai-Juan; Wang, Chang-Yun
• Is Part Of: Natural product research. Volume 32:Issue 2(2018)
• Page Start: 208
• Page End: 213
• Publication Date: 2018-01-17
• Subjects: Mangrove -- endophytic fungus -- Daldinia eschscholtzii -- cytochalasin; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1346641
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: One new cytochalasin metabolite [11]-cytochalasa-5(6), 13-diene-1, 21-dione-7, 18-dihydroxy-16, 18-dimethyl-10-phenyl-(7 S *, 13 E, 16 S *, 18 R *) (1 ), together with three known compounds (2 –4 ) were obtained from the EtOAc extract of the endophytic fungus Daldinia eschscholtzii HJ001 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds1 and2 were evaluated for their antibacterial and cytotoxic activities. Abstract :