A highly sensitive and fast responsive naphthalimide-based fluorescent probe for Cu2+ and its application. (8th November 2017)

• Record Type: Journal Article
• Authors: Zhang, Beibei; Qin, Fengyun; Niu, Huawei; Liu, Yao; Zhang, Di; Ye, Yong
• Is Part Of: New journal of chemistry. Volume 41:Number 23(2017)
• Page Start: 14683
• Page End: 14688
• Publication Date: 2017-11-08
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c7nj02813j
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : The response of the probe L to Cu 2+ is reversible and very fast (20 s).L has a low detection limit of 49 nM and was used for imaging of Cu 2+ in MCF-7 cells with satisfying results. The sensorL can be analyzed with a molecular logic gate. Abstract : A novel naphthalimide-based Cu 2+ fluorescent probe containing diglycolamine, which served as a water solubility group and provided the coordination ability to Cu 2+, was designed and successfully synthesized. The response of the probeL to Cu 2+ is reversible and very fast (20 s). The low detection limit of 49 nM for Cu 2+ detection was sufficient for the detection of the maximum allowed copper levels in dietary and environmental sources. The stoichiometry of binding betweenL and Cu 2+ was 1 : 1, as supported by fluorescence spectra and ESI-MS.L has been used for the imaging of Cu 2+ in MCF-7 cells with satisfying results. The sensorL can be analyzed with a molecular logic gate. It was also found that the fluorescence ofL -Cu 2+ can be regulated by a photoacid.