Occupation and chronic obstructive pulmonary disease in Minsk tractor plant workers. Issue 12 (20th September 2017)

• Record Type: Journal Article
• Authors: Vinnikov, Denis; Semizhon, Sergey; Rybina, Tatsyana; Savich, Ludmila; Scherbitsky, Vicktor; Manichev, Igor
• Is Part Of: American journal of industrial medicine. Volume 60:Issue 12(2017)
• Page Start: 1049
• Page End: 1055
• Publication Date: 2017-09-20
• Subjects: COPD -- dust -- occupational -- smoking -- spirometry -- TSP; Medicine, Industrial -- Periodicals; Médecine du travail -- Périodiques; 616.9803
• DOI: 10.1002/ajim.22776
• Languages: English
• ISSNs: 0271-3586

Abstract

Abstract : Background: The aim of this study was to measure the association of exposure to dust at workplace with COPD using objective methods of exposure and outcome classification. Methods: Forced expiratory volume in one second (FEV1 ) to forced vital capacity (FVC) <70%; FVC below LLN, and FEV1 below LLN from the annual screening of Minsk Tractor Plant workers ( N = 458) were tested for predictors in an adjusted logistic regression model. Results: In a regression model, adjusted for pack‐years of smoking, age, sex, and work duration, work in highly exposed workplaces was associated with FEV1 /FVC<70% (odds ratio (OR) 2.10 (95% confidence interval (CI) 1.16;3.83); and FEV1 <LLN (OR 2.24 (95% CI 1.18;4.25)). Given the fraction of workers exposed 0.20, population attributable fraction (PAF%) of COPD due to dust exposure was 18%. Conclusions: Workers in highly exposed to dust workplaces had double odds of developing COPD.