Lentigo maligna of the face: A quantitative simple method to identify individual patient risk probability on dermoscopy. (7th June 2017)

• Record Type: Journal Article
• Authors: Carbone, Anna; Ferrari, Angela; Paolino, Giovanni; Buccini, Pierluigi; De Simone, Paola; Eibenschutz, Laura; Piemonte, Paolo; Silipo, Vitaliano; Sperduti, Isabella; Catricalà, Caterina; Frascione, Pasquale
• Is Part Of: Australasian journal of dermatology. Volume 58:Number 4(2017)
• Page Start: 286
• Page End: 291
• Publication Date: 2017-06-07
• Subjects: dermoscopy -- lentigo maligna -- lichen planus‐like keratosis -- pigmented actinic keratosis -- pigmented facial lesions -- solar lentigo; Dermatology -- Periodicals; Dermatology -- Australasia -- Periodicals; 616.5005
• DOI: 10.1111/ajd.12595
• Languages: English
• ISSNs: 0004-8380

Abstract

Abstract: Background/Objectives: The clinical and dermoscopic differential diagnosis of flat pigmented facial lesions represents a great challenge for the clinicians. Our aim was to report a quantitative method based on dermoscopic features to better classify pigmented facial lesions. Methods: This is a retrospective case‐series study that analysed the dermoscopic features of 582 pigmented facial lesions. Results: The individual patient probability of lentigo maligna (LM) was predicted by a multivariate model, with an accuracy of 0.72. According to the odds ratio at the multivariate analysis, an individual scoring index was assigned to each criterion, and a value of 4.56 was identified as optimal cut‐off point. Up to a score of 2.5, the probability that a lesion is an LM is 0. The probability increases from 10 to 50% for a score ranging between 4.5 and 6. It is about 90% for a score of 7. Conclusion: The optimal cut‐off point obtained and the curve that identifies the probability of a patient having a LM could improve the classification and the management strategies of equivocal pigmented facial lesions.