Five new indole derivatives from the cyanobacterium Moorea producens. (December 2017)

• Record Type: Journal Article
• Authors: Jiang, Weina; Bu, Yingyue; Kawaguchi, Mioko; Osada, Hiroki; Fukuoka, Masayuki; Uchida, Hajime; Watanabe, Ryuichi; Suzuki, Toshiyuki; Nagai, Hiroshi
• Is Part Of: Phytochemistry letters. Volume 22(2017:Dec.)
• Page Start: 163
• Page End: 166
• Publication Date: 2017-12
• Subjects: Cyanobacteria -- Moorea producens -- Indole -- Structural elucidation -- Bioactivity; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2017.09.025
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Five new indole derivatives were isolated from the cyanobacterium Moorea producen s. Their structures were determined by 1D and 2D NMR spectroscopy and HR-ESI–MS. Five new compounds did not show any bioactivity at the tested concentration. Abstract: Chemical analysis of the hydrophilic fraction from marine cyanobacterium Moorea producens extracts led to the isolation of five new indole derivatives (1 -5 ). So far, 2-formyl-4, 5, 6, 7-tetrahydroindole has been reported only for6 from the nature, consequently compounds1 -5 were the second representatives of this class. Cytotoxicity, diatom growth inhibition, and antibacterial activity tests for compounds1 -5 showed no bioactivity at the concentration tested.