Relation of Angiographic Thrombus Burden With Electrocardiographic Grade III Ischemia in Patients With ST-Segment Elevation Myocardial Infarction. (January 2014)

• Record Type: Journal Article
• Authors: Kurt, Mustafa; Karakas, Mehmet Fatih; Buyukkaya, Eyup; Akçay, Adnan Burak; Sen, Nihat
• Is Part Of: Clinical and applied thrombosis/hemostasis. Volume 20:Number 1(2014:Jan.)
• Page Start: 31
• Page End: 36
• Publication Date: 2014-01
• Subjects: thrombus burden -- ST-elevation myocardial infarction -- grade III ischemia; Hemostasis -- Periodicals; Thrombosis -- Periodicals; 616.13
• DOI: 10.1177/1076029613476340
• Languages: English
• ISSNs: 1076-0296

Abstract

Background: We aimed to investigate the association between electrocardiographic (ECG) grade III ischemia and angiographic thrombus burden in patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI). Methods: The study population consisted of 307 patients with STEMI. Baseline ECGs of the patients were analyzed for grade III ischemia; angiographic thrombus burden was assessed by thrombolysis in myocardial infarction thrombus classification. Results: A total of 108 (35%) patients had low thrombus burden whereas 199 (65%) patients had high thrombus burden. Grade III ischemia was more prevalent in patients with high thrombus burden (25.1% vs 11.1%, P = .004). Only grade III ischemia (odds ratio: 2.59, 95% confidence interval 1.24-5.39, P = .011) and history of coronary artery disease (CAD) were found to be the independent predictors of high thrombus burden. Conclusion: Grade III ischemia on ECG and previous history of CAD were independent predictors of coronary thrombus burden in patients with STEMI who underwent pPCI.