Nanomaterials to microplastics: Swings and roundabouts. (December 2017) - Scott-Fordsmand, J.J.
Graphical abstract: Highlights: Risk assessment (RA) of product-embedded nanomaterials emphasized as more realistic. This approach mainly relies on testing fragmented nano-containing products. This makes the RA more challenging than conventional approaches. Hazard testing of fragments is very difficult and is currently not feasible for small organisms. Fragment tests may give short-term exposure insight but neglect long-term effects. Abstract: In recent years, the testing of nanomaterials during their use in products has been increasingly emphasized, as this will provide a more realistic risk assessment (RA) compared with RA based on pristine nanomaterials. We show that (i) using such an approach for a "realistic" RA is increasing the complexity of the RA, (ii) several testing-aspects render this approach more challenging than the conventional methods, (iii) interpretation of the results becomes difficult, and (iv) the resulting RA may need to be evaluated carefully as it yields improved understanding of the short-term fate of the individual product, but long-term consequences may be neglected.