Cell Imaging: In Situ Ligation of High‐ and Low‐Affinity Ligands to Cell Surface Receptors Enables Highly Selective Recognition (Adv. Sci. 11/2017). Issue 11 (23rd November 2017)

• Record Type: Journal Article
• Authors: Taichi, Misako; Nomura, Shogo; Nakase, Ikuhiko; Imamaki, Rie; Kizuka, Yasuhiko; Ota, Fumi; Dohmae, Naoshi; Kitazume, Shinobu; Taniguchi, Naoyuki; Tanaka, Katsunori
• Is Part Of: Advanced science. Volume 4:Issue 11(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-11-23
• Subjects: cell imaging -- cell surfaces -- glycan -- in situ ligation; Science -- Periodicals; 505
• DOI: 10.1002/advs.201770057
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : An entirely unexplored concept of simultaneously recognizing two receptors using high‐ and low‐affinity ligands is developed in article number1700147 by Katsunori Tanaka and co‐workers. Ligating them in situ on the target cell surface offers a new paradigm for visualizing target cells with a high imaging contrast.