An optimized protocol for anthraquinones isolation from Rhamnus frangula L. Issue 3 (1st February 2018)

• Record Type: Journal Article
• Authors: Gonçalves, Renato Sonchini; Silva, Expedito Leite; Hioka, Noboru; Nakamura, Celso Vataru; Bruschi, Marcos Luciano; Caetano, Wilker
• Is Part Of: Natural product research. Volume 32:Issue 3(2018)
• Page Start: 366
• Page End: 369
• Publication Date: 2018-02-01
• Subjects: Optimised isolation -- column chromatography -- chrysophanol -- physcione -- emodine -- Rhamnus frangula L.; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1356836
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Different from works described in the literature, which use expansive analytical methods to separation of anthraquinones derivatives (AQs), this communication reported a simple and inexpensive methodology to get them. In this way, the expensive commercial AQs: Chrysophanol, physcione and emodine were extracted from plant material ( Rhamnus frangula L.) and isolated by classical column chromatography technique under optimised binary mobile phase gradients (CHCl3 : AcOEt( a ), a = 1 to 5%) in excellent yields. Abstract :