Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris. Issue 4 (December 2017)

• Record Type: Journal Article
• Authors: Moore, G.; Schelenz, S.; Borman, A.M.; Johnson, E.M.; Brown, C.S.
• Is Part Of: Journal of hospital infection. Volume 97:Issue 4(2017)
• Page Start: 371
• Page End: 375
• Publication Date: 2017-12
• Subjects: Candida auris -- Quantitative suspension test -- Chlorine -- Chlorhexidine gluconate -- Povidone-iodine; Cross infection -- Periodicals; Cross infection -- Prevention -- Periodicals; Nosocomial infections -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Cross Infection -- Periodicals; Cross Infection -- prevention & control -- Periodicals; Infection Control -- Periodicals; Electronic journals; 614.44
• DOI: 10.1016/j.jhin.2017.08.019
• Languages: English
• ISSNs: 0195-6701

Abstract

Summary: Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans . When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol.