CT MR image registration for 3D image based treatment planning in cervical cancer brachytherapy – An initial experience. (October 2017)

• Record Type: Journal Article
• Authors: Dzingwa, Admire; Hayes, Eamonn
• Is Part Of: Physica medica. Volume 42(2017)
• Page Start: 355
• Publication Date: 2017-10
• Subjects: Medical physics -- Periodicals; Biophysics -- Periodicals; Biophysics -- Periodicals; Imagerie médicale -- Périodiques; Radiothérapie -- Périodiques; Rayons X -- Sécurité -- Mesures -- Périodiques; Physique -- Périodiques; Médecine -- Périodiques; 610.153
• DOI: 10.1016/j.ejmp.2017.05.012
• Languages: English
• ISSNs: 1120-1797

Abstract

Abstract : The use of image registration is relevant in radiotherapy centres with good access to computed tomography (CT) and limited access to magnetic resonance (MR) imaging. This presentation outlines recent work on commissioning and bringing into clinical use CT MR image registration to facilitate 3 dimensional image based treatment planning in cervical cancer high dose rate brachytherapy. CT MR compatible ring and tandem applicators are required for this dual imaging approach. X-ray catheters and MR line markers were fitted into the applicators as appropriate for the imaging modality. Applicator reconstruction, dose prescription, organ at risk (OAR) contouring and optimisation were performed on the CT images. Contouring of the high risk clinical target volume was performed on the MR images. Image registration involved identifying and marking three corresponding points on the ring and tandem applicator on both the CT images and the MR images. The average error associated with the registration in all three patients involved in this study was less than 1 mm. Treatment plans were generated that complied with published dose volume parameters for the target and OAR dose constraints[1, 2] . CT MR image registration was shown to be feasible for delivering high quality cervical cancer brachytherapy treatments and shows a distinct improvement on CT only treatments.