A rare case of a pericardial mass: Myelosarcoma from relapsed acute monoblastic leukaemia without bone marrow involvement. Issue 4 (25th October 2017)

• Record Type: Journal Article
• Authors: Binny, Simon; Tomlinson, Stephen; Hammett, Christopher; Dahiya, Arun; Pillai, Elango; Prasad, Sandhir B.
• Is Part Of: Australasian journal of ultrasound in medicine. Volume 20:Issue 4(2017)
• Page Start: 178
• Page End: 180
• Publication Date: 2017-10-25
• Subjects: myelosarcoma -- myeloid sarcoma -- pericardial mass -- leukaemia -- tamponade; Ultrasonics in medicine -- Periodicals; Ultrasonic imaging -- Periodicals; Ultrasonic imaging; Ultrasonics in medicine; Periodicals; 616.075430
• DOI: 10.1002/ajum.12073
• Languages: English
• ISSNs: 1836-6864

Abstract

Abstract: Introduction: A 67‐year‐old male presented with progressive exertional dyspnoea, night sweats and 25 kg of weight loss over 2 years. He was febrile, 38.0°C, hypotensive and tachycardiac. Pulsus paradoxus was present. His electrocardiogram showed electrical alternans. He had previously had acute myeloid leukaemia treated with three cycles of chemotherapy. Results: The patient was found to have a 3.6 cm pericardial effusion with features consistent with tamponade and three cardiac masses (largest 10 × 9 × 5 cm) and mediastinal lymphadenopathy. He had 825 mL of pericardial fluid drained from which cytology was consistent with extramedullary leukaemia. A bone marrow aspirate and trephine was normal. Conclusion: The findings suggested extramedullary recurrence of leukaemia in the pericardium, without bone marrow involvement.