Unprecedented One‐Pot Reaction towards Chiral, Non‐Racemic Copper(I) Complexes of [2.2]Paracyclophane‐Based P, N‐Ligands. Issue 65 (27th October 2017)

• Record Type: Journal Article
• Authors: Braun, Carolin; Nieger, Martin; Bräse, Stefan
• Is Part Of: Chemistry. Volume 23:Issue 65(2017)
• Page Start: 16452
• Page End: 16455
• Publication Date: 2017-10-27
• Subjects: chirality -- copper -- cross-coupling -- cyclophanes -- phosphanes; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201704115
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Herein, we report a simple one‐pot route to enantiopure copper(I) complexes featuring a unique [2.2]paracyclophane‐based P, N ‐ligand system. Phosphine and pyridine moieties can be varied allowing the modular synthesis of these rigid and stable [2.2]paracyclophane‐based P, N ‐ligands. These P, N ‐ligands are a new ligand class for different transition‐metal complexes, which is shown exemplarily for palladium(II). Abstract : Phosphination instead of Stille cross‐coupling : With [2.2]paracyclophane‐based P, N ‐ligands, a new ligand motif is readily accessible through a one‐pot synthesis of the respective copper(I) complexes. The enantiopure synthesis of these chiral complexes enables convenient approach towards the enantiopure free ligands.