Late‐onset hemophagocytic lymphohistiocytosis with neurological presentation. Issue 11 (12th September 2017)

• Record Type: Journal Article
• Authors: Benezech, Sarah; Walzer, Thierry; Charrier, Emily; Heidelberg, Damien; De Saint‐Basile, Geneviève; Bertrand, Yves; Belot, Alexandre
• Is Part Of: Clinical case reports. Volume 5:Issue 11(2017)
• Page Start: 1743
• Page End: 1749
• Publication Date: 2017-09-12
• Subjects: Hemophagocytic lymphohistiocytosis -- late‐onset -- neurology -- perforin; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.1135
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Missense mutations in genes involved in familial hemophagocytic lymphohistiocytosis can delay the onset of this life‐threatening disease. In children and adults, early recognition of aspecific features as neurological symptoms is crucial as urgent treatment is required. Abstract : Missense mutations in genes involved in familial hemophagocytic lymphohistiocytosis can delay the onset of this life‐threatening disease. In children and adults, early recognition of aspecific features as neurological symptoms is crucial as urgent treatment is required.