ChemInform Abstract: Transition Metal Free Intramolecular Selective Oxidative C(sp3)‐N Coupling: Synthesis of N‐Aryl‐Isoindolinones from 2‐Alkylbenzamides. Issue 24 (June 2015)

• Record Type: Journal Article
• Authors: Verma, Ajay; Patel, Saket; Meenakshi, Meenakshi; Kumar, Amit; Yadav, Abhimanyu; Kumar, Shailesh; Jana, Sadhan; Sharma, Shubham; Prasad, Ch. Dunga; Kumar, Sangit
• Is Part Of: ChemInform. Volume 46:Issue 24(2015)
• Page Start: no
• Page End: no
• Publication Date: 2015-06
• Subjects: indole derivatives, isoindole derivatives -- ring closure reactions, annulation reactions -- amination, N‐alkylation, N‐arylation; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201524134
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The synthesis of important drugs such as indoprofen (XIV) and DWP205190 (XI) is achieved from less expensive 2‐methylbenzoic acid in two steps, resp., without employing brominating or reducing agent.