Boronic acid-based chemical sensors for saccharides. (27th November 2017)

• Record Type: Journal Article
• Authors: Zhang, Xiao-tai; Liu, Guang-jian; Ning, Zhang-wei; Xing, Guo-wen
• Is Part Of: Carbohydrate research. Volume 452(2017)
• Page Start: 129
• Page End: 148
• Publication Date: 2017-11-27
• Subjects: Saccharides -- Boronic acids -- Detection -- Fluorescence -- Assembly; Carbohydrates -- Periodicals; Chemistry, Organic -- Periodicals; Biochemistry -- Periodicals; Carbohydrates -- Periodicals; Chimie organique -- Périodiques; Glucides -- Périodiques; Biochemistry; Carbohydrates; Chemistry, Organic; Periodicals; Electronic journals; 507.78
• DOI: 10.1016/j.carres.2017.10.010
• Languages: English
• ISSNs: 0008-6215

Abstract

Abstract: During the past decades, the interaction between boronic acids-functionalized sensors and saccharides is of great interest in the frontier domain of the interdiscipline concerning both biology and chemistry. Various boronic acid-based sensing systems have been developed to detect saccharides and corresponding derivatives in vitro as well as in vivo, which embrace unimolecular sensors, two-component sensing ensembles, functional assemblies, and boronic acid-loaded nanomaterials or surfaces. New sensing strategies emerge in endlessly with excellent selectivity and sensitivity. In this review, several typical sensing systems were introduced and some promising examples were highlighted to enable the deep insight of saccharides sensing on the basis of boronic acids. Graphical abstract: Highlights: Unimolecular sensors including monoboronic acid and di-/multi-boronic acids were designed for detecting saccharides. Two-component sensing systems were fabricated for saccharides discrimination. Assembly-based sensing systems was well explored for saccharides recognition. Boronic acid-functionalized nanomaterials and surfaces have been achieved for saccharides sensing.