Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts. Issue 10 (27th June 2017)

• Record Type: Journal Article
• Authors: Mancuso, Raffaella; Amuso, Roberta; Armentano, Biagio; Grasso, Giuseppe; Rago, Vittoria; Cappello, Anna Rita; Galiano, Francesco; Figoli, Alberto; De Luca, Giorgio; Hoinkis, Jan; Gabriele, Bartolo
• Is Part Of: ChemPlusChem. Volume 82:Issue 10(2017)
• Page Start: 1235
• Page End: 1244
• Publication Date: 2017-06-27
• Subjects: antifouling membranes -- antimicrobial polymers -- organic synthesis -- polymerizable quaternary ammonium salts -- quaternary ammonium salts; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cplu.201700194
• Languages: English
• ISSNs: 2192-6506

Abstract

Abstract: This study reports an efficient and practical synthetic approach for the synthesis of a particularly important class of polymerizable quaternary ammonium salts (PQASs), that is, acryloxyalkyltriethylammonium bromides (AATEABs), which may find application as antimicrobial coatings for commercial membranes with antifouling and anti‐biofouling properties, to be used for wastewater treatment. The synthetic method is based on a simple two‐step procedure from commercially available substrates, entirely carried out under air and without any need for chromatographic purification. All the newly synthesized AATEABs were tested for their antimicrobial activity, and the results showed that AATEABs bearing an alkyl chain of 11 and particularly 12 carbon atoms possessed significant activity against Gram positive bacteria and yeast strains. Abstract : Antimicrobial activity : Novel efficient synthetic approaches to polymerizable quaternary ammonium salts (acryloxyalkyltriethylammonium bromides, AATEABs; see figure) with antimicrobial activity are reported, which are useful precursors for developing nanostructured membranes with anti‐biofouling properties in wastewater treatment.