Pristine carbon nanotube scaffolds for the growth of chondrocytes. Issue 41 (16th October 2017)

• Record Type: Journal Article
• Authors: King, Alice A. K.; Matta-Domjan, Brigitta; Large, Matthew J.; Matta, Csaba; Ogilvie, Sean P.; Bardi, Niki; Byrne, Hugh J.; Zakhidov, Anvar; Jurewicz, Izabela; Velliou, Eirini; Lewis, Rebecca; La Ragione, Roberto; Dalton, Alan B.
• Is Part Of: Journal of materials chemistry. Volume 5:Issue 41(2017)
• Page Start: 8178
• Page End: 8182
• Publication Date: 2017-10-16
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c7tb02065a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes. Abstract : The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.