Gelatin Solubility and Processing in Ionic Liquids: An Approach Towards Waste to Utilization. Issue 31 (2nd November 2017)

• Record Type: Journal Article
• Authors: J Mehta, Mohit; Bharmoria, Pankaj; Bhayani, Khushbu; Kumar, Arvind
• Is Part Of: ChemistrySelect. Volume 2:Issue 31(2017)
• Page Start: 9895
• Page End: 9900
• Publication Date: 2017-11-02
• Subjects: antimicrobial activity -- biopolymer -- gelatin -- Ionic liquids -- proteins; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201702015
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: We have investigated the solubility behavior of protein gelatin, in neat protic ionic liquids (ILs) [alkyl ammonium nitrates, ([Cn NH3 ][NO3 ], n= 2, 3, 4)] and their reciprocal binary mixtures with [C4 mim][Cl](1‐butyl‐3‐methyl imidazolium chloride). Very high dissolution of gelatin could be achieved in [C2 NH3 ][NO3 ](Ethylammonium nitrate). High solvating ability of [C2 NH3 ][NO3 ] towards gelatin was utilized to process solid pharmaceutical waste of gelatin capsules by dissolving in [C2 NH3 ][NO3 ] for the recovery of pure gelatin. The recovered gelatin was further processed to prepare gelatin/Ag2 O nano‐composite in a mixed IL system, [C2 NH3 ][NO3 ]+[C4 mim][Cl]. The prepared nano‐composite exhibited excellent antimicrobial activity on gram negative bacteria pseudomonas aeruginosa MTCC NO‐1688 and Escherichia coli MTCC NO‐42 and therefore, can be useful for potential biomedical applications. The developed process is a worthy alternative strategy for "waste to utilization" of gelatin pharmaceutical scrap. Abstract : Very high solubility (87%) of protein gelatin is achieved in ionic liquid [C2 NH3 ][NO3 ]. This concept is utilized to extract pure gelatin from waste gelatin capsules. Ag2 O/gelatin nanocomposite having very good antimicrobial property is synthesised from waste gealtin capsules using DSIL system [C2 NH3 ][NO3 ]+[C4 mim][Cl].