Recent Advances on Bioactive Constituents in Ferula. Issue 7 (8th August 2017)

• Record Type: Journal Article
• Authors: Zhou, Yueting; Xin, Fang; Zhang, Guoqiang; Qu, Hexiang; Yang, Desong; Han, Xiaoqiang
• Is Part Of: Drug development research. Volume 78:Issue 7(2017)
• Page Start: 321
• Page End: 331
• Publication Date: 2017-08-08
• Subjects: ferula -- coumarins -- sesquiterpene‐substituted compounds -- daucane esters -- biological activity; Drug development -- Periodicals; Drugs -- Research -- Periodicals; 615.19
• DOI: 10.1002/ddr.21402
• Languages: English
• ISSNs: 0272-4391

Abstract

ABSTRACT: Preclinical Research The genus Ferula ( Umbelliferea ) is widely distributed across Central Asia and the Mediterranean. Some plants of the genus Ferula have been used as sources of pharmaceuticals for centuries. Ferula is a rich source of biologically active compounds, including coumarin derivatives, sesquiterpene‐substituted compounds, daucane esters, humulane, and germacrane compounds, aromatic lactones and disulfide compounds. Therefore, utilizing these bioactive constituents with antimicrobial and insecticidal effects not only can provide a new strategy for developing drug and green pesticide, but also protect endangered plant resources. In the present review, research advances on the bioactive constituents of the genus Ferula the plant sources. Drug Dev Res 78 : 321‐331, 2017. © 2017 Wiley Periodicals, Inc.