Clinicopathologic Characteristics of Elderly with Gastric Cancer, and the Risk Factors of Postoperative Complications. (2nd November 2017)

• Record Type: Journal Article
• Authors: Li, Yong; Tan, Bibo; Fan, Liqiao; Zhao, Qun; Tan, Ming; Wang, Dong; Jia, Nan; Liu, Qingwei
• Is Part Of: Journal of investigative surgery. Volume 30:Number 6(2017)
• Page Start: 394
• Page End: 400
• Publication Date: 2017-11-02
• Subjects: gastric cancer -- elderly -- clinicopathologic characteristics -- surgical treatment -- postoperative complication; Surgery -- Research -- Periodicals; Research; Surgery; Surgical Procedures, Operative; 617.075
• DOI: 10.1080/08941939.2016.1265617
• Languages: English
• ISSNs: 0894-1939

Abstract

ABSTRACT: Purpose : In China, gastric cancer (GC), which is one of the most common malignant tumors, has an increasing incidence in elderly population due to aging process. Since a considerable number of elderly patients with GC accepting surgical treatments developed postoperative complications, it is necessary to evaluate risk factors for postoperative complications. Materials and methods : In the present study, the clinicopathologic characteristics of 3, 024 elderly patients (aged ≥65 years) with GC, who underwent surgery between 1996 and 2006, were examined and contributing factors for postoperative complications were analyzed. A total of 2, 915 non-elderly patients (aged <65 years) with GC during the same period were enrolled as a control group. Clinicopathologic characteristics of non-elderly patients were investigated and compared with elderly group. Results : As to clinicopathologic characteristics, significant differences were detected in terms of location of primary lesions between elderly patients and non-elderly patients ( p <.05), whereas no statistical difference was observed in other characteristics between two groups ( p >.05). Surgical property and method in elderly patients were similar to that in non-elderly patients ( p >.05). Regression analysis showed that diabetes, chronic pulmonary disease, preoperative anemia, preoperative hypoalbuminemia, combined organ excision, and blood transfusion were independent factors for complications in elderly patients ( p <.05), with some differences from non-elderly group. Conclusions : Elderly group with GC had distinctive clinicopathologic characteristics. Surgery remains principal treatment for elderly, and proper preoperative measures are required to decrease postoperative complications.