Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles for two-photon photodynamic therapy or photoacoustic imaging. Issue 43 (30th October 2017)

• Record Type: Journal Article
• Authors: Mauriello-Jimenez, Chiara; Henry, Maxime; Aggad, Dina; Raehm, Laurence; Cattoën, Xavier; Wong Chi Man, Michel; Charnay, Clarence; Alpugan, Serkan; Ahsen, Vefa; Tarakci, Deniz Kutlu; Maillard, Philippe; Maynadier, Marie; Garcia, Marcel; Dumoulin, Fabienne; Gary-Bobo, Magali; Coll, Jean-Luc; Josserand, Véronique; Durand, Jean-Olivier
• Is Part Of: Nanoscale. Volume 9:Issue 43(2017)
• Page Start: 16622
• Page End: 16626
• Publication Date: 2017-10-30
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c7nr04677d
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles (BSPOR and BSPHT) were prepared. Abstract : Porphyrin- or phthalocyanine-bridged silsesquioxane nanoparticles (BSPOR and BSPHT) were prepared. Their endocytosis in MCF-7 cancer cells was shown with two-photon excited fluorescence (TPEF) imaging. With two-photon excited photodynamic therapy (TPE-PDT), BSPOR was more phototoxic than BSPHT, which in contrast displayed a very high signal for photoacoustic imaging in mice.