Programming membrane permeability using integrated membrane pores and blockers as molecular regulators. Issue 91 (1st November 2017)
- Record Type:
- Journal Article
- Title:
- Programming membrane permeability using integrated membrane pores and blockers as molecular regulators. Issue 91 (1st November 2017)
- Main Title:
- Programming membrane permeability using integrated membrane pores and blockers as molecular regulators
- Authors:
- Thomas, Julia M.
Friddin, Mark S.
Ces, Oscar
Elani, Yuval - Abstract:
- Abstract : Vesicle permeability could be tuned using α-hemolysin pores and varying concentrations of TRIMEB blockers, which act as molecular regulators Abstract : We report a bottom-up synthetic biology approach to engineering vesicles with programmable permeabilities. Exploiting the concentration-dependent relationship between constitutively active pores (alpha-hemolysin) and blockers allows blockers to behave as molecular regulators for tuning permeability, enabling us to systematically modulate cargo release kinetics without changing the lipid fabric of the system.
- Is Part Of:
- Chemical communications. Volume 53:Issue 91(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 91(2017)
- Issue Display:
- Volume 53, Issue 91 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 91
- Issue Sort Value:
- 2017-0053-0091-0000
- Page Start:
- 12282
- Page End:
- 12285
- Publication Date:
- 2017-11-01
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc05423h ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 5334.xml