A phosphine-free, heterogeneous palladium-catalyzed atom-efficient carbonylative cross-coupling of triorganoindiums with aryl halides leading to unsymmetrical ketones. (27th October 2017)

• Record Type: Journal Article
• Authors: You, Shengyong; Xiao, Ruian; Liu, Haiyi; Cai, Mingzhong
• Is Part Of: New journal of chemistry. Volume 41:Number 22(2017)
• Page Start: 13862
• Page End: 13870
• Publication Date: 2017-10-27
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c7nj02969a
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A phosphine-free heterogeneous palladium-catalyzed carbonylative cross-coupling of triorganoindiums with aryl halides for the synthesis of unsymmetrical ketones has been described. Abstract : The first phosphine-free heterogeneous palladium-catalyzed carbonylative cross-coupling of aryl halides with triorganoindiums has been developed that proceeds smoothly under 1 or 2.5 atm of carbon monoxide in THF at 68 °C and provides a general and powerful tool for the synthesis of various valuable unsymmetrical ketones with high atom-economy, good yield, and recyclability of the catalyst. Our system not only avoids the use of phosphine ligands, but also solves the basic problem of palladium catalyst recovery and reuse.