First graphene oxide promoted metal-free nitrene insertion into olefins in water: towards facile synthesis of activated aziridines. Issue 77 (17th October 2017)

• Record Type: Journal Article
• Authors: Shukla, Prashant; Mahata, Suhasini; Sahu, Anjumala; Singh, Manorama; Rai, Vijai K.; Rai, Ankita
• Is Part Of: RSC advances. Volume 7:Issue 77(2017)
• Page Start: 48723
• Page End: 48729
• Publication Date: 2017-10-17
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra09351a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A facile metal-free graphene oxide (GO)-catalyzed synthesis of tosylaziridines using PhINTs as the nitrene source is reported. Abstract : A facile metal-free graphene oxide (GO)-catalyzed synthesis of tosylaziridines using PhINTs as the nitrene source is reported. The reaction involves nitrene insertion into a variety of styrene/nitrostyrene derivatives in the presence of iodine at room temperature and in water. The envisaged process is highly green, operationally simple, it employs metal-free catalysis and it affords excellent yields (85–92%) and high diastereoselectivity (95–98%) of the Z -isomer of the product. The catalyst used could be recycled for further use in other reactions.