Synthesis and characterization of a biphenyl-linked hemicryptophane and an endohedral cobalt(II) complex. Issue 48 (29th November 2017)

• Record Type: Journal Article
• Authors: Makita, Yoshimasa; Danno, Tomofumi; Ikeda, Keisuke; Lee, Hsien-Han; Abe, Taro; Sogawa, Kento; Nomoto, Akihiro; Fujiwara, Shin-ichi; Ogawa, Akiya
• Is Part Of: Tetrahedron letters. Volume 58:Issue 48(2017)
• Page Start: 4507
• Page End: 4509
• Publication Date: 2017-11-29
• Subjects: Hemicryptophane -- Cyclotriveratrylene -- Molecular cage -- Endohedral complex; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2017.10.039
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: A rigid biphenyl-linked hemicryptophane is synthesized. An endohedral cobalt(II) hemicryptophane complex is also obtained. The cobalt(II) complex has three components within the cavity. Abstract: Hemicryptophanes are covalent molecular cages, constructed from a cyclotriveratrylene-based host unit and a functional unit linked by covalent spacers, which have been designed to accommodate endohedral functionalities in the cavity. In this study, the synthesis and characterization of the rigid, biphenyl-linked hemicryptophane1 were investigated by NMR, ESI-MS, and X-ray crystallography. The structure of the inclusion complex, in which a dichloromethane molecule was constructed encapsulated within1, was characterized by X-ray crystallography. An endohedral, cobalt(II) hemicryptophane complex2 was also synthesized and characterized ESI-MS and X-ray crystallography. The X-ray crystal structure of2 showed that the biphenyl-linked hemicryptophane had three components—a molecule each of chloroform and acetonitrile, and a cobalt(II) ion—within its cavity.