A single stranded fluorescent peptide probe for targeting collagen in connective tissues. Issue 87 (18th October 2017)

• Record Type: Journal Article
• Authors: Cai, Xiangdong; Liu, Zhao; Zhao, Sha; Song, Chen; Dong, Shouliang; Xiao, Jianxi
• Is Part Of: Chemical communications. Volume 53:Issue 87(2017)
• Page Start: 11905
• Page End: 11908
• Publication Date: 2017-10-18
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc06056d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A novel single stranded fluorescent collagen mimetic peptide has been constructed by introducing a bulky FAM dye in the central region rather than the N terminus. Without the need for any prior thermal or ultraviolet treatment, the peptide probe can be conveniently applied to specifically target collagen in connective tissues for fluorescence imaging. Abstract : We herein report the construction of a novel single stranded fluorescent collagen mimetic peptide by introducing a bulky FAM dye in the central region rather than the N terminus. Without the need for any prior thermal or ultraviolet treatment, the peptide probe can be conveniently applied to specifically target collagen in connective tissues for fluorescence imaging.