Ethnicity influences pain after ultrasound-guided percutaneous liver biopsy. Issue 12 (December 2015)

• Record Type: Journal Article
• Authors: Mahadeva, Sanjiv; Mahfudz, Anis S.; Vijayananthan, Anushya
• Is Part Of: European journal of gastroenterology & hepatology. Volume 27:Issue 12(2015:Dec.)
• Publication Date: 2015-12
• Subjects: complications -- ethnicity -- liver biopsy -- pain -- ultrasound guided; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; Digestive organs -- Diseases; Liver -- Diseases; Periodicals; 616.33
• DOI: 10.1097/MEG.0000000000000465
• Languages: English
• ISSNs: 0954-691X

Abstract

Abstract : Background: The influence of ethnicity on pain complicating ultrasound-guided percutaneous liver biopsy (US-guided PLB) and its clinical impact has not been reported to date. Methods: Consecutive adults from a multiethnic background, undergoing an US-guided PLB, were independently assessed for pain up to 6 h after the procedure. Clinical and demographic parameters were analysed to determine independent predictors of significant pain after PLB. Willingness to undergo a repeat procedure was assessed 1 week after PLB. Results: Data from 203 patients (median age 50 years; 43.9% female; ethnicity: Malay 41.5%, Chinese 40%, Indian 18%; median BMI 27.7 kg/m 2 ; median waist circumference 92.0 cm) were analysed. Pain after US-guided PLB was experienced in 133 (61.1%) patients, with severity grades as follows: none, n =81 (39.9%); mild, n =56 (27.6%); moderate, n =51 (25.1%); and severe, n =15 (7.4%). Analgesia requirements correlated well with severity of pain. Independent predictors of significant pain after PLB (moderate and severe categories) in patients included age less than 50 years [odds ratio (OR) 3.0], female sex (OR 3.7), Indian ethnicity (OR 2.9) and Malay ethnicity (OR 2.7), but not number of needle passes, BMI and educational levels. Patients who experienced moderate/severe pain were less willing to undergo a repeat PLB compared with those who experienced mild/no pain (60.9 vs. 82.8%, P =0.001). Conclusion: Ethnicity has an important role in the development of pain after US-guided PLB. This has a significant impact on willingness to repeat the procedure.