90Y Liver Radioembolization Imaging Using Amplitude-Based Gated PET/CT. (May 2017)

• Record Type: Journal Article
• Authors: Osborne, Dustin R.; Acuff, Shelley; Neveu, Melissa; Kaman, Austin; Syed, Mumtaz; Fu, Yitong
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 5(2017)
• Publication Date: 2017-05
• Subjects: 90Y dosimetry -- gating -- motion correction -- PET/CT -- radioembolization -- yttrium; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001613
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: The usage of PET/CT to monitor patients with hepatocellular carcinoma following 90 Y radioembolization has increased; however, image quality is often poor because of low count efficiency and respiratory motion. Motion can be corrected using gating techniques but at the expense of additional image noise. Amplitude-based gating has been shown to improve quantification in FDG PET, but few have used this technique in 90 Y liver imaging. The patients shown in this work indicate that amplitude-based gating can be used in 90 Y PET/CT liver imaging to provide motion-corrected images with higher estimates of activity concentration that may improve posttherapy dosimetry.