Pectic polysaccharide from the green fruits of Momordica charantia (Karela): structural characterization and study of immunoenhancing and antioxidant properties. (12th January 2015)

• Record Type: Journal Article
• Authors: Panda, Bibhash C.; Mondal, Soumitra; Devi, K. Sanjana P.; Maiti, Tapas K.; Khatua, Somanjana; Acharya, Krishnendu; Islam, Syed S.
• Is Part Of: Carbohydrate research. Volume 401(2015)
• Page Start: 24
• Page End: 31
• Publication Date: 2015-01-12
• Subjects: Momordica charantia -- Pectic polysaccharide -- Structure -- NMR studies -- Immunoactivation -- Antioxidant activities; Carbohydrates -- Periodicals; Chemistry, Organic -- Periodicals; Biochemistry -- Periodicals; Carbohydrates -- Periodicals; Chimie organique -- Périodiques; Glucides -- Périodiques; Biochemistry; Carbohydrates; Chemistry, Organic; Periodicals; Electronic journals; 507.78
• DOI: 10.1016/j.carres.2014.10.015
• Languages: English
• ISSNs: 0008-6215

Abstract

Graphical abstract: Highlights: Pectic polysaccharide (PS) was isolated and purified from the fruits of Momordica charantia (Karela). Its structure was established by chemical and 1D/2D NMR studies. This molecule exhibited immunoenhancing properties. It also showed antioxidant properties. Abstract: A water soluble pectic polysaccharide (PS) isolated from the aqueous extract of the green fruits of Momordica charantia containsd -galactose andd -methyl galacturonate in a molar ratio of nearly 1:4. It showed splenocyte, thymocyte as well as macrophage activations . Moreover, it exhibited potent antioxidant activities. On the basis of total acid hydrolysis, methylation analysis, periodate oxidation, and 1D and 2D NMR studies, the structure of the repeating unit of the pectic polysaccharide was established as: