Myxoid liposarcoma of the supraglottic larynx, the first Scandinavian case. Issue 1 (1st January 2016) - Nygren, Alexander
Abstract: With less than 40 cases in the English literature, liposarcomas of the upper aerodigestive tract are extremely rare. We present the first Scandinavian case: a 72-year-old male with progressive dysphagia and dysphonia. Tumour was located in the left aryepiglottic fold, 4–5 mm with normal epithelium. Tumour was excised macroscopically radical and histology showed myxoid liposarcoma, grade I. The patient received adjuvant radiotherapy. The gold standard is core needle or excisional biopsy. Main treatment remains surgery and the use of adjuvant radiotherapy is debatable. Liposarcomas have a high rate of recurrence and a tendency of de-differentiation over time; therefore, long-term follow-up is recommended. The diagnosis can only be made histologically and preferably with FISH probes.