A combination of Yiqiqubai granule and 308-nm excimer laser in treatment of segmental vitiligo: a prospective study of 233 patients. (3rd October 2017)

• Record Type: Journal Article
• Authors: Zhang, Chengzhong; Zhou, Le; Huang, Jie; Shi, Weimin
• Is Part Of: Journal of dermatological treatment. Volume 28:Number 7(2017)
• Page Start: 668
• Page End: 671
• Publication Date: 2017-10-03
• Subjects: Segmental vitiligo -- Yiqiqubai granule -- 308-nm excimer laser; Skin -- Diseases -- Treatment -- Periodicals; Skin Diseases -- drug therapy -- Periodicals; Skin Diseases -- therapy -- Periodicals; 616.5
• DOI: 10.1080/09546634.2017.1303570
• Languages: English
• ISSNs: 0954-6634

Abstract

Abstract: Objective: To study the effect of Yiqiqubai granule combined with 308-nm excimer laser treatment for segmental vitiligo (SV). Methods: A prospective research was performed in 233 patients with SV treated in Shanghai General Hospital from 11 February 2015 to 25 August 2016, they were divided into group A ( n = 75), group B ( n = 78) and group C ( n = 80) according to the random number table. Group A was treated with Yiqiqubai granule, group B treated with 308-nm excimer laser and group C treated with combined treatments. The treatment time lasts for 6 months. The clinical efficacy, color-reverse rate and quality of life of the three groups were assessed. Results: After treatment, the effective rate and markedly effective rate of group C (87.5%, 51.3%) were significantly higher than group A (74.7%, 42.7%) and group B (80.8%, 47.4%) ( p < .05). Color-reverse rate of group C (66.5 ± 17.6%) was much higher than group A (47.2 ± 16.4%) and group B (49.9 ± 24.2%) ( p < .05). Significant differences were found among three groups after treatment in terms of embarrassment, social and work ( p < .05). Conclusions: The combination of 308-nm excimer laser and Yiqiqubai granule in the treatment of SV has good clinical effect.