Do CVD grown graphene films have antibacterial activity on metallic substrates?. (April 2015)

• Record Type: Journal Article
• Authors: Dellieu, L.; Lawarée, E.; Reckinger, N.; Didembourg, C.; Letesson, J.-J.; Sarrazin, M.; Deparis, O.; Matroule, J.-Y.; Colomer, J.-F.
• Is Part Of: Carbon. Volume 84(2015)
• Page Start: 310
• Page End: 316
• Publication Date: 2015-04
• Subjects: Carbon -- Periodicals; Carbone -- Périodiques; Koolstof; Toepassingen; Electronic journals; 546.681
• DOI: 10.1016/j.carbon.2014.12.025
• Languages: English
• ISSNs: 0008-6223

Abstract

Abstract: Accurate assessment of the antibacterial activity of graphene requires consideration of both the graphene fabrication method and, for supported films, the properties of the substrate. Large-area graphene films produced by chemical vapor deposition were grown directly on copper substrates or transferred on a gold substrate and their effect on the viability and proliferation of the Gram-positive bacteria Staphylococcus aureus and the Gram-negative bacteria Escherichia coli were assessed. The viability and the proliferation of both bacterial species were not affected when they were grown on a graphene film entirely covering the gold substrate, indicating that conductivity plays no role on bacterial viability and graphene has no antibacterial activity against S. aureus and E. coli . On the other hand, antibacterial activity was observed when graphene coated the copper substrates, resulting from the release of bactericidal cupric ions in inverse proportion to the graphene surface coverage.