Current and future applications of corneal cross-linking. Issue 3 (May 2015)

• Record Type: Journal Article
• Authors: Khandelwal, Sumitra S.; Randleman, J. Bradley
• Is Part Of: Current opinion in ophthalmology. Volume 26:Issue 3(2015:May)
• Publication Date: 2015-05
• Subjects: accelerated corneal cross-linking -- corneal cross-linking -- cross-linking -- ectasia -- infectious keratitis -- keratoconus; Ophthalmology -- Periodicals; Eye Diseases -- Indexes; Eye Diseases -- Periodicals; Review Literature -- Indexes; Review Literature -- Periodicals; Vision Disorders -- Indexes; Vision Disorders -- Periodicals; 617.7
• DOI: 10.1097/ICU.0000000000000146
• Languages: English
• ISSNs: 1040-8738

Abstract

Abstract : Purpose of review: To review current concepts and future directions of corneal cross-linking (CXL) as a treatment for keratoconus, ectasia after refractive surgery and infectious keratitis. Recent findings: Several important laboratory and clinical studies have established the safety and success of corneal cross-linking for the treatment of keratoconus and other corneal ectasias. Recently, additional studies have analyzed new directions and controversies in corneal cross-linking, exploring new indications, comparing new techniques and analyzing results of new protocols. Summary: The results of bench and clinical research are providing the foundation to allow for protocol modifications of the standard cross-linking protocols and expansion of cross-linking concepts for techniques such as accelerated cross-linking, epithelium-sparing protocols and measurement of progression and success.