New supramolecular metallo-terpyridine carboxymethyl cellulose derivatives with antimicrobial properties. (13th February 2015)

• Record Type: Journal Article
• Authors: Hassan, Enas A.; Hassan, Mohammad L.; Moorefield, Charles N.; Newkome, George R.
• Is Part Of: Carbohydrate polymers. Volume 116(2015)
• Page Start: 2
• Page End: 8
• Publication Date: 2015-02-13
• Subjects: Carboxymethyl cellulose -- Terpyridine -- Supramolecular -- Antimicrobial; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2014.06.056
• Languages: English
• ISSNs: 0144-8617

Abstract

Highlights: New water soluble supramolecular cellulose derivative was prepared. Carboxymethyl cellulose was reacted with Cu II –terpyridine complex. The prepared CMC–Cu II –terpyridine derivative has antibacterial properties. Abstract: Preparation of a new water-soluble, cellulose derivative via a supramolecular route is presented. In a one-step procedure, carboxymethyl cellulose (CMC) was reacted with the Cu(BF4 )2 complex of 4′-chloro[2, 2′:6′, 2″]terpyridine to generate the desired CMC–Cu II –terpyridine derivative. This polymeric salt was characterized by elemental analysis, ultraviolet–visible spectroscopy (UV–visible), Fourier transform infrared (FTIR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), rheological properties measurements, thermogravimetric analysis (TGA), dynamic mechanical thermal analysis (DMTA), and tensile strength properties testing. In addition, antimicrobial properties were demonstrated against Gram-positive bacteria ( Staphylococcus aureus and Streptococcus thermophilus ), Gram-negative bacteria ( Escherichia coli ), and yeast ( Saccharomyces cervisiae ). The minimum inhibitory concentration of the prepared metallo-terpyridine CMC derivative against the studied microorganisms ranged from 6 to 8 mg/L to achieve ≥90% of microbial growth inhibition.