Umbilical Granuloma in a 2-Month-Old Patient: Histopathology of a Common Clinical Entity. (February 2016)

• Record Type: Journal Article
• Authors: Brady, Mary; Conway, Andrea B.; Zaenglein, Andrea L.; Helm, Klaus F.
• Is Part Of: American journal of dermatopathology. Volume 38:Number 2(2016)
• Publication Date: 2016-02
• Subjects: umbilical granuloma -- umbilical granuloma histopathology -- umbilical abnormalities; Skin -- Diseases -- Periodicals; Histology, Pathological -- Periodicals; 616.50705
• DOI: 10.1097/DAD.0000000000000429
• Languages: English
• ISSNs: 0193-1091

Abstract

Abstract : Abstract: Umbilical granulomas are the most common anomaly of the umbilicus in neonates and infants. These lesions are characterized by an overgrowth of granulation tissue that persists at the base of the umbilical cord after its separation. Histologically, they consist of granulation tissue, which is composed of fibroblasts, inflammatory cells, and vascular endothelial cells set in an edematous stroma. Although umbilical granulomas are commonly seen clinically, there are no reports of their histopathology in the literature. The authors present the histology of this clinical finding in a 2-month-old infant, as it is important for the pathologist to be aware of this benign entity and distinguish it from other umbilical anomalies that may be of greater clinical significance.