A case of adult‐onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome in Japan. (2nd May 2017)

• Record Type: Journal Article
• Authors: Yasuura, Shusuke; Harada, Yukinori
• Is Part Of: Journal of general and family medicine. Volume 18:Number 5(2017)
• Page Start: 261
• Page End: 264
• Publication Date: 2017-05-02
• Subjects: adult -- auto‐inflammatory disease -- cimetidine -- Japanese -- periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome; Primary care (Medicine) -- Periodicals; Family medicine -- Periodicals; Family Practice; Primary Health Care; Japan; Periodicals; 610
• DOI: 10.1002/jgf2.51
• Languages: English
• ISSNs: 2189-7948

Abstract

Abstract: Adult‐onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is rare. We report the case of a 23‐year‐old woman with PFAPA syndrome in Japan. Her symptoms lasted for approximately 5 days in each period regardless of nonsteroidal anti‐inflammatory drug or antibiotic treatment. She was diagnosed with PFAPA syndrome based on her periodic self‐limiting symptoms and no evidence of other febrile diseases. Following cimetidine therapy, her periodic symptoms diminished. PFAPA syndrome should be considered in patients presenting with periodic fever and upper respiratory symptoms regardless of their age or ethnicity.