Silver doped titanium dioxide nanoparticles as antimicrobial additives to dental polymers. Issue 3 (March 2017)

• Record Type: Journal Article
• Authors: Chambers, C.; Stewart, S.B.; Su, B.; Jenkinson, H.F.; Sandy, J.R.; Ireland, A.J.
• Is Part Of: Dental materials. Volume 33:Issue 3(2017)
• Page Start: e115
• Page End: e123
• Publication Date: 2017-03
• Subjects: Silver doped titanium oxide -- Resin -- Antimicrobial; Dentistry -- Periodicals; Dental materials -- Periodicals; 617.695
• DOI: 10.1016/j.dental.2016.11.008
• Languages: English
• ISSNs: 0109-5641

Abstract

Highlights: Ag doping of TiO2 results in a band gap shift towards the visible spectrum. Small quantities of Ag–TiO2 have a bactericidal effect on S. mutans under visible light conditions. Although reduced, the bactericidal effect was still observed when Ag–TiO2 was embedded in polymer. Abstract: Objective: The objectives of this in vitro study were to produce a filled resin containing Ag–TiO2 filler particles and to test its antibacterial properties. Methods: Ag–TiO2 particles were manufactured using the ball milling method and incorporated into an epoxy resin using a high speed centrifugal mixer. Using UV/vis spectrophotometry investigations were performed to assess how the photocatalytic properties of the Ag–TiO2 particles are affected when encased in resin. Adopting the bacteria colony counting technique, the antibacterial properties of Ag–TiO2 particles and Ag–TiO2 containing resins were assessed using Streptococcus mutans under varying lighting conditions. Results: Ag doping of TiO2 results in a band gap shift towards the visible spectrum enabling Ag–TiO2 to exhibit photocatalytic properties when exposed to visible light. Small quantities of Ag–TiO2 were able to produce a bactericidal effect when in contact with S. mutans under visible light conditions. When incorporated into the bulk of an epoxy resin, the photocatalytic properties of the Ag–TiO2 particles were significantly reduced. However, a potent bactericidal effect was still achieved against S. mutans . Significance: Ag–TiO2 filled resin shows promising antimicrobial properties, which could potentially be used clinically.