Transient and Reproducible Loss of Motor-Evoked Potential Signals After Intravenous Levetiracetam in a Child Undergoing Craniotomy for Resection of Astrocytoma. (15th January 2015)

• Record Type: Journal Article
• Authors: Simpao, Allan F.; Janik, Luke S.; Hsu, Grace; Schwartz, Alan Jay; Heuer, Gregory G.; Warrington, Andrew P.; Rehman, Mohamed A.
• Is Part Of: A & A case reports. Volume 4:Number 2(2015)
• Publication Date: 2015-01-15
• Subjects: Anesthesiology -- Periodicals; Anesthesia -- Periodicals; Anesthesiology; Analgesia; Anesthesiology; Periodicals; 617.9605
• DOI: 10.1213/XAA.0000000000000107
• Languages: English
• ISSNs: 2325-7237

Abstract

Abstract : Transcranial electrical motor-evoked potential (tceMEP) monitoring is used in complex intracranial and spinal surgeries to detect and prevent neurological injury. We present a case of transient, reproducible loss of tceMEPs after an infusion of levetiracetam during craniotomy and tumor resection in a child. Cessation of the infusion resulted in restoration of baseline tceMEPs. When the infusion was resumed at the end of the procedure, a similar decrease in tceMEPs was seen as before, after the infusion was stopped. The surgery and postoperative course proceeded without incident, and the patient experienced a full recovery.