Validation of a Behavioral Approach for Measuring Saccades in Parkinson's Disease. Issue 6 (2nd November 2017)

• Record Type: Journal Article
• Authors: Turner, Travis H.; Renfroe, Jenna B.; Duppstadt-Delambo, Amy; Hinson, Vanessa K.
• Is Part Of: Journal of motor behavior. Volume 49:Issue 6(2017)
• Page Start: 657
• Page End: 667
• Publication Date: 2017-11-02
• Subjects: behavioral test -- cognition -- dementia -- eye tracking -- mild cognitive impairment -- Parkinson's disease -- saccade -- saccadic eye movements; Human mechanics -- Periodicals; Movement, Psychology of -- Periodicals; Motor Activity -- Periodicals; Motor Skills -- Periodicals; Bewegingsleer; Mécanique humaine -- Périodiques; Psychomotricité -- Périodiques; 612.705
• DOI: 10.1080/00222895.2016.1250720
• Languages: English
• ISSNs: 0022-2895

Abstract

ABSTRACT: Speed and control of saccades are related to disease progression and cognitive functioning in Parkinson's disease (PD). Traditional eye-tracking complexities encumber application for individual evaluations and clinical trials. The authors examined psychometric properties of standalone tasks for reflexive prosaccade latency, volitional saccade initiation, and saccade inhibition (antisaccade) in a heterogeneous sample of 65 PD patients. Demographics had minimal impact on task performance. Thirty-day test–retest reliability estimates for behavioral tasks were acceptable and similar to traditional eye tracking. Behavioral tasks demonstrated concurrent validity with traditional eye-tracking measures; discriminant validity was less clear. Saccade initiation and inhibition discriminated PD patients with cognitive impairment. The present findings support further development and use of the behavioral tasks for assessing latency and control of saccades in PD.