Early severe preeclampsia with marked platelet dysfunction in association with essential thrombocytemia: case report and discussion. Issue 7 (October 2015)

• Record Type: Journal Article
• Authors: Onisai, Minodora; Voican, Irina; Ciorascu, Mihai; Popov, Viola; Bumbea, Horia; Gaman, Mihaela; Filipescu, Alexandru; Vladareanu, Radu; Vladareanu, Ana-Maria
• Is Part Of: Blood coagulation and fibrinolysis. Volume 26:Issue 7(2015)
• Publication Date: 2015-10
• Subjects: essential thrombocytemia -- platelet dysfunction -- preeclampsia; Blood -- Coagulation -- Periodicals; Fibrinolysis -- Periodicals; Hemostasis -- Periodicals; Thrombosis -- Periodicals; Blood Coagulation -- Periodicals; Fibrinolysis -- Periodicals; Hemostasis -- Periodicals; Thrombosis -- Periodicals; 612.115
• DOI: 10.1097/MBC.0000000000000352
• Languages: English
• ISSNs: 0957-5235

Abstract

Abstract : Essential thrombocytemia – a classic myeloproliferative neoplasm characterized by persistent thrombocytosis – may associate both thrombotic and hemorrhagic events, as well as platelet dysfunction. Of all myeloproliferative neoplasms, essential thrombocytemia is more likely to be associated with pregnancy, because of a higher comparative incidence in younger patients. This association significantly increases the risk of pregnancy loss and of various pregnancy complications. We present a case of early severe preeclampsia with a critical and unusual evolution and life-threatening complications.