Fluorogenic nanoreactor assembly with boosted sensing kinetics for timely imaging of cellular hydrogen peroxide. Issue 6 (9th November 2015)

• Record Type: Journal Article
• Authors: Heo, Jeongyun; Lim, Chang-Keun; Kim, Youngsun; Cho, Hong-Jun; Lee, Yong-Deok; Maeng, Joon-ho; Ahn, Dae-Ro; Lee, Sangyoup; Bang, Joona; Park, Soo Young; Kim, Sehoon
• Is Part Of: Chemical communications. Volume 52:Issue 6(2016)
• Page Start: 1131
• Page End: 1134
• Publication Date: 2015-11-09
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc06387f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Nanoscopic catalysis: a reactor-like nanoprobe with enzyme-like boosted sensing kinetics is reported. Abstract : The precise detection of endogenous H2 O2 has been considered to be a useful tool for understanding cell physiology. Here, we have developed a nanoreactor co-incorporated with a H2 O2 -responsive fluorogenic molecule and a catalytic additive. The fast sensing kinetics allows us to visualize a subcellular response in real-time.