A light sensitive self-assembled nanogel as a tecton for protein patterning materials. Issue 6 (26th November 2015)

• Record Type: Journal Article
• Authors: Nishimura, Tomoki; Takara, Masahiro; Mukai, Sada-atsu; Sawada, Shin-ichi; Sasaki, Yoshihiro; Akiyoshi, Kazunari
• Is Part Of: Chemical communications. Volume 52:Issue 6(2016)
• Page Start: 1222
• Page End: 1225
• Publication Date: 2015-11-26
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc08416d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A light-sensitive ortho -nitrobenzyl unit on the hydroxyl group of pullulan. The use of light-sensitive components makes it possible to create patterned nanogels that can immobilize proteins. Abstract : A self-assembled nanogel is constructed from light-sensitive cholesteryl pullulan (Ls-CHP) by using photo-labile ortho -nitrobenzyl ( o -NB) units. The nanogel-based film is obtained by evaporation of an Ls-CHP nanogel solution. Exposure of the resulting nanogel-based film to light with a mask resulted in a patterned film that can encapsulate FITC-insulin.