One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment. Issue 2 (15th December 2015)

• Record Type: Journal Article
• Authors: Martin, Robert. C.; Locatelli, Erica; Li, Yan; Matteini, Paolo; Monaco, Ilaria; Cui, Guozhen; Li, Suping; Banchelli, Martina; Pini, Roberto; Comes Franchini, Mauro
• Is Part Of: Journal of materials chemistry. Volume 4:Issue 2(2016)
• Page Start: 207
• Page End: 211
• Publication Date: 2015-12-15
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c5tb02499d
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : A biocompatible nanosystem made up of a chitosan and filled with Mg NPs was synthesized and tested as tool for photothermal therapy. Proof of concept on hcc-bearing mice is presented. Abstract : A novel highly biocompatible nanosystem made up of a chitosan matrix and filled with magnesium nanoparticles was synthesized using a simple and one-pot strategy, and tested as a promising, well-tolerated tool for photothermal therapy. Moreover, in vivo a proof of concept on hepatocarcinoma-bearing mice is presented.