Palladium-catalyzed direct coupling of 2-vinylanilines and isocyanides: an efficient synthesis of 2-aminoquinolines. Issue 47 (12th October 2015)

• Record Type: Journal Article
• Authors: Wang, Lijie; Ferguson, Jamie; Zeng, Fanlong
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 47(2015)
• Page Start: 11486
• Page End: 11491
• Publication Date: 2015-10-12
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob01659b
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A variety of 2-aminoquinolines were prepared in good to excellent yields. Abstract : Palladium-catalyzed oxidative coupling of 2-vinylanilines and isocyanides constitutes a direct, facile, and efficient approach to 2-aminoquinolines. The procedure, employing palladium acetate and silver carbonate, is attractive in terms of assembly efficiency, functional group tolerance, and operational simplicity. A variety of 2-aminoquinolines were prepared in good to excellent yields.