A model of poststroke fatigue based on sensorimotor deficits. Issue 6 (December 2015)

• Record Type: Journal Article
• Authors: Kuppuswamy, Annapoorna; Rothwell, John; Ward, Nick
• Is Part Of: Current opinion in neurology. Volume 28:Issue 6(2015:Dec.)
• Publication Date: 2015-12
• Subjects: inflammation -- poststroke fatigue -- sensorimotor deficits; Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; 616.805
• DOI: 10.1097/WCO.0000000000000260
• Languages: English
• ISSNs: 1473-6551

Abstract

Abstract : Purpose of review: This review examines recent studies in poststroke fatigue that might contribute in understanding the pathophysiology of poststroke fatigue. Poststroke fatigue is a common problem in stroke survivors. Little is known about the pathophysiology of chronic fatigue in stroke survivors. It has long been thought of as a neuropsychiatric problem. However, there is gathering evidence to the contrary. In this study, we propose a new model of poststroke fatigue based on recent findings of corticomotor neurophysiological, behavioural, and perceptual deficits in the poststroke fatigue population. Summary: The current evidence suggests that poststroke fatigue may not be a neuropsychiatric problem but a problem of the sensorimotor system. Future studies need to address the causal link between sensorimotor deficits and poststroke fatigue.